综合征的预测

HELLP综合征是妊娠高血压疾病，子痫前期的严重的并发症，表现为溶血、肝功能损害和血小板减少，对母胎均造成严重影响。了解疾病的发病机制并预测其发病是我们面临的重要课题之一。中井章人等探讨了超声测量肝脏血流量预测HELLP综合征的方法，发现正常孕妇28周后肝脏血流量有意义增多，主要是门脉回流增加，反映了随孕周增加循环血流量增加。妊娠高血压综合征重度子痫前期时门脉血流量明显减少，肝动脉血流代偿性增加，维持肝脏总血流量。HELLP综合征发病前4天内超声检查，结果门脉、肝动脉血流量均明显减少，与没有HELLP综合征的妊娠高血压疾病比较门脉血流量有意义减少，肝脏循环失代偿，总的肝脏血流量明显减少，出现肝功能损害。

（夏晓艳）

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